|Linoleic acid and ulcerative colitis
||[Feb. 7th, 2010|12:04 pm]
Discusses alternatives for immune disorders
Gut 2009;58:1606-1611 doi:10.1136/gut.2008.169078
Inflammatory bowel disease
Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case–control study within a European prospective cohort study
1. The IBD in EPIC Study Investigators
1. Correspondence to Dr A Hart, University of East Anglia, Norwich, NR4 7TJ, UK; email@example.com
* Revised 21 May 2009
* Accepted 6 June 2009
* Published Online First 23 July 2009
The main finding of this study was more than a doubling of the risk of ulcerative colitis with the highest intake of the dietary n-6 PUFA, linoleic acid. If the association is causative then 30% of all cases could be attributed to such higher intakes.
Mod note: Correlation is not causation, but there is a statistically significant correlation between high consumption of linoleic acid and the development of ulcerative colitis.
Linoleic acid is found mainly in vegetable oils, according to Wikipedia. But in reading most of the entry, you will find that linoleic acid is found most often in grains -- wheat, corn, rice. The next highest source is nuts and seeds.
Factory produced meat will also be high in linoleic acid, because mainstream meat production involves heavy grain consumption, which is stored in the fat of said animals.
This could explain the success of the Specific Carbohydrate Diet in treating colitis and Crohn's disease. No grains are allowed on the SCD, and nuts and seeds are limited (even in the form of nut and seed butters).